Affiliation:
1. Department of Mathematics Wollega University Nekemte ETHIOPIA
Abstract
In this study, a nonlinear deterministic mathematical model of Human Papillomavirus was formulated. The model is studied qualitatively using the stability theory of differential equations. The model is analyzed qualitatively for validating the existence and stability of disease ¬free and endemic equilibrium points using a basic reproduction number that governs the disease transmission. It's observed that the model exhibits a backward bifurcation and the sensitivity analysis is performed. The optimal control problem is designed by applying Pontryagin maximum principle with three control strategies viz. prevention strategy, treatment strategy, and screening strategy. Numerical results of the optimal control model reveal that a combination of prevention, screening, and treatment is the most effective strategy to wipe out the disease in the community.
Publisher
World Scientific and Engineering Academy and Society (WSEAS)
Subject
Artificial Intelligence,General Mathematics,Control and Systems Engineering
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