Cytogenetic Examination of Human Peripheral Blood Lymphocytes Cryopreserved after Gamma Irradiation: A Pilot Study

Author:

Suto Yumiko1,Tominaga Takako2,Akiyama Miho1,Hirai Momoki1

Affiliation:

1. Department of Radiation Measurement and Dose Assessment, Center for Advanced Radiation Emergency Medicine, National Institutes for Quantum and Radiological Science and Technology

2. Department of Radiation Emergency Management, Center for Advanced Radiation Emergency Medicine, National Institutes for Quantum and Radiological Science and Technology

Publisher

International Society of Cytology

Subject

Cell Biology,Plant Science,Genetics,Animal Science and Zoology

Reference16 articles.

1. Borràs-Fresneda, M., Barquinero, J., Gomolka, M., Hornhardt, S., Rössler, U., Armengol, G. and Barrios, L. 2016. Differences in DNA repair capacity, cell death and transcriptional response after irradiation between a radiosensitive and a radioresistant cell line. Sci. Rep. 6: 27043.

2. Chambrette, V., Laroche, P., Lataillade, J. J. and Voisin, P. 1996. Technical report: Effect of cryopreservation on chromosomal aberration yield in irradiated lymphocytes. Int. J. Radiat. Biol. 70: 671–675.

3. Darroudi, F., Fomina, J., Meijers, M. and Natarajan, A. T. 1998. Kinetics of the formation of chromosome aberrations in x-irradiated human lymphocytes, using PCC and FISH. Mutat. Res. 404: 55–65.

4. Duthie, S. J., Pirie, L., Jenkinson, A. McE. and Narayanan, S. 2002. Cryopreserved versus freshly isolated lymphocytes in human biomonitoring: Endogenous and induced DNA damage, antioxidant status and repair capability. Mutagenesis 17: 211–214.

5. International Atomic Energy Agency 2001. Cytogenetic Analysis for Radiation Dose Assessment. A Manual. Technical Report Series No. 405. IAEA Publications, Vienna.

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