A case of rhinolaryngoscleroma in a patient with neurofibromatosis type 1

Abstract

EnAbstract Introduction Scleroma is a chronic-specific granuloma of the nose and it may involve other parts of the respiratory tract. The condition is endemic in Egypt. Neurofibromatosis type 1 (NF-1) is one of the most common genetic conditions of the nervous system. Before this report, no case had been published documenting scleroma in a patient with NF-1. Aim To describe a case of rhinolaryngoscleroma in a patient with NF-1. Methods Case report and literature review. Results Presentation of clinical, imaging and pathological findings, as well as management considerations. Conclusion This is the first case to be reported in the literature documenting the coexistence of rhinolaryngoscleroma and NF-1. The biological events in the immune system await further studies.