Author:
Aref Wael M.,Hosni Noha A.,Naguib Mohamed,El-Basel Mohamed
Abstract
Abstract
Background
Liver cirrhosis is a condition that destroys the normal function of the liver, leading to hepatic encephalopathy, which is associated with impairment in postural control and disturbance in balance.
Aim of the study
The aim of this study was to detect the disturbances in balance and postural control because of hepatic encephalopathy as a result of liver cirrhosis using dynamic posturography.
Participants and methods
Individuals were divided into two groups: 45 patients with liver cirrhosis and 45 controls. Both groups underwent dynamic posturography to evaluate balance control, number connection test-type A, line tracing test, and serum ammonia (NH3) level to assess encephalopathy.
Results
Dynamic posturography findings were significantly weaker in patients with liver cirrhosis than in the controls. They were also weaker in patients with high NH3 than in patients with low NH3. There were significant negative correlations between dynamic posturography findings and number connection test-type A, line tracing test, and NH3 levels.
Conclusion
Hepatic encephalopathy because if liver cirrhosis affects balance control and the degree of affection is related to the degree of encephalopathy.
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Developmental Biology,Embryology,Anatomy,General Earth and Planetary Sciences,General Environmental Science
Reference17 articles.
1. Sorrell MF, Belongia EA, Costa J, Gareen IF, Grem JL, Inadomi JM, et al. National Institutes of Health Consensus Development Conference Statement: management of hepatitis B. Ann Intern Med 2009; 150:104–110.
2. Abdel-wahab MF, Zakaria S, Kamel M, Abdell-Khaliq MK, Mabrouk MA, Salama H, et al. High seroprevalence of hepatitis C infection among risk groups in Egypt. Am J Trop Med Hyg 1994; 51:563–567.
3. Ong JP, Mullen KD. Hepatic encephalopathy. Eur J Gastroenterol Hepatol 2001; 13:325–334.
4. Groeneweg MQ, Uero JC, De Bruijn I, Hartmann IJ, Essinkbot ML, Hop WC, et al. Subclinical hepatic encephalaopathy impairs daily functioning. Hepa-tology 1998; 28:45–49.
5. Mei-Yun L, Chia-Ling C, Yu-Cheng P, Chau-Peng L, Yiu-Chung LM, et al. Comparison of the static and dynamic balance performance in young, middle-aged, and elderly healthy people. Chang Gung Med J 2009; 32:297–304.