TELOMERE LENGTH, SEVERITY OF CORONAVIRUS INFECTION AND PREMATURE AGING (LITERATURE REVIEW)

Author:

I.V. Mironov1ORCID,A.V. Gordienko1ORCID,D.Yu. Serdyukov1ORCID,B.A. Chumak1ORCID,V.V. Yakovlev1ORCID

Affiliation:

1. Military medical academy named after S.M. Kirov, Petersburg, Russian Federation

Abstract

Abstract. According to modern concepts, telomere length is one of the most reliable indicators of a person's overall health. It is associated with a predisposition to longevity or to diseases associated with age, such as hypertension, atherosclerosis, coronary heart disease and others. International experience in predicting the course of the disease caused by a new coronavirus infection (COVID-19) has shown that the likelihood of a severe course of the disease in elderly patients is inversely proportional to the patient's telomere length. The available scientific data allow us to consider telomere length as a biological predictor of assessing the severity of pneumonia caused by the SARS-CoV-2 virus.

Publisher

Technomed Holdings LLC

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