LOCAL TREATMENT OF INFECTED WOUNDS DEPENDING ON THE PHASE OF THE WOUND PROCESS

Abstract

Despite the availability of a large number of funds for the treatment of infected wounds, this issue of clinical medicine does not lose its relevance. In most cases, a combined method of wound treatment is used, which implies both the use of systemic drugs and local treatment, which, taking into account the phase of the wound process, should be aimed at cleansing, reducing inflammation, stimulating regeneration. At the present stage of the development of medicine, dressings used in surgery should meet the principle of wound healing in a humid environment and have certain requirements: to restrain the ingress of microorganisms into the wound, the composition of dressings should not include components that have toxic, allergic, mutagenic and carcinogenic effects. Recently, considerable progress has been made in the development of new methods of treating infected wounds, which are based on the impact of chemical and physical factors on the healing process, taking into account a personalized approach to the patient, based primarily on his general condition and the ability of the body to resist infection. The review, based on modern literature data, presents a generalized analysis of the use of dosage forms and wound coatings in various phases of the wound process, with an emphasis on phase I as the most aggressive for the macroorganism. The criterion for evaluating the correct treatment is to reduce the time of wound healing and prevent the development of complications. An important modern criterion for the effectiveness of wound healing is the aesthetic appearance of the scar, which encourages the search for new ways to treat wounds, a combination of already known drugs and the continuation of research in the field of wound coatings.