FEATURES OF DISORDERS OF THE MOTOR FUNCTION OF THE STOMACH WITH DYSREGENERATIVE CHANGES IN ITS MUCOUS MEMBRANE

Author:

I.M. Pavlovich1ORCID,G.A. Alper1ORCID,D.V. Nosovich1ORCID,B.A. Chumak1ORCID

Affiliation:

1. Military medical academy named after S.M. Kirov, St. Petersburg, Russian Federation

Abstract

The study was conducted at the Department and Clinic of Hospital Therapy of the Military Medical Academy. CM. Kirov. The work studied the relationship of motor disorders of the stomach with morphological changes in the gastric mucosa in 90 patients with chronic atrophic gastritis and 93 patients with chronic non-atrophic gastritis aged 20 to 73 years (the average age of patients was 52.7+1.7 years and 48.5+ 3.6 respectively). Motor disorders were characteristic of 87% of patients with chronic atrophic gastritis and 79.6% of patients with chronic non-atrophic gastritis. It was found that in patients with chronic atrophic gastritis significantly more often (p<0.01) than in patients with chronic non-atrophic gastritis, there was an insufficiency of the lower esophageal sphincter. At the same time, insufficiency of the pylorus in comparison with its spasm was significantly more often (p<0.01) detected in chronic atrophic gastritis. Duodenogastric reflux in combination with insufficiency of the lower esophageal sphincter in patients with chronic atrophic gastritis significantly more often (p<0.01) atrophy was observed in the body and antrum of the stomach. When atrophy was localized only in the antrum, pyloric insufficiency was observed significantly more often than spasm (p<0.01). Duodenogastric reflux in combination with insufficiency of lower esophageal sphincter in patients with chronic atrophic gastritis significantly more often (p<0,01) atrophy in the body and antral part of the stomach was observed. Thus, the relationship between insufficiency of the lower esophageal and pyloric sphincters with a diffuse atrophic process has been established.

Publisher

Technomed Holdings LLC

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference16 articles.

1. A modern approach to the management and treatment of patients with precancerous conditions and changes in the gastric mucosa / I.M. Pavlovich, I.L. Pegasheva, G.A. Alper, V.A. Yudin // Bulletin of the Russian Military Medical Academy. 2020; № 2(70): 222-226. EDN HFOHPL.

2. Pavlovich, I.M. Precancerous potential of chronic atrophic gastritis associated with Helicobacter pylori infection, preventive measures / I.M. Pavlovich, V.Yu. Golofeevsky, V.P. Kalinovsky // Problems of oncology. 2006; T. 52 (2): 223-229. EDN KVXSLB.

3. Katchieva, P.H. Clinical characteristics of patients with atrophic gastritis / P.H. Katchieva // Modern science: current issues, achievements and innovations. Collection of articles of the International Scientific and Practical Conference. 2018; P. 138-141.

4. Kaprin A.D., Starinsky V.V., Shakhzadova A.O. Malignant neoplasms in Russia in 2021 (morbidity and mortality). Moscow: P.A. Herzen Institute of Medical Research – Branch of the Federal State Budgetary Institution "NMIC of Radiology" of the Ministry of Health of Russia. 2022; 252 p.

5. Plummer, M. Global burden of stomach cancer caused by pylori / M. Plummer, K. Iseki, M. Tatsuta // Int. J. Cancer. 2015; No. (136): P. 487-490. DOI: 10.1002/ijc.28999

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3