Affiliation:
1. Peoples' Friendship University of Russia, Moscow, Russian Federation
2. Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russian Federation
Abstract
In modern pharmacy, to expand the range of herbal preparations, food spicy-oil raw materials are increasingly used, which for many centuries have been used as a source of medicines. Which raw materials include the leaves of the noble laurel, used to obtain essential oils and extraction preparations. An analysis of the historical literature revealed the widespread use of both the raw material itself and the preparations derived from it for the treatment of various inflammatory diseases, fevers, and as a prophylactic during epidemics. It should be noted that this raw material was included in the Russian pharmacopoeias from I to VII editions. Unfortunately, at the moment the raw material is not pharmacopoeial, which determines the relevance of research on the study of biologically active substances and pharmacological activity of this raw material. Standardization of laurel leaves in the Russian Federation is carried out according to the requirements of the regulatory documentation of the food industry. In the course of studying the scientific literature and patent documentation, a significant number of works devoted to the study of the antibacterial, fungicidal, antioxidant activity of the biologically active substances of the leaves and fruits of the noble laurel, due to the content of such classes of substances as terpenoids, flavonoids, polyphenols, were revealed. A detailed study of the features of the biosynthesis of terpinoids in the leaves of common laurel, as well as their identification and determination of functional characteristics, was carried out. The revealed results make it possible to consider the raw material - laurel leaves as a promising source of obtaining new medicines, and scientific research aimed at systematizing the available data, forming a strategy for analyzing the authenticity and good quality of this raw material with the subsequent development of regulatory documentation as a promising and relevant area of pharmaceutical analysis.
Subject
General Earth and Planetary Sciences,General Environmental Science
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