Metaplastic breast cancer: A case report and literature review

Author:

Y Ibrahim Dalia1,Osman Lojayne2

Affiliation:

1. College of Arts and Sciences, The Ohio State University, Columbus, OH 43210, USA

2. Department of Pathology, University of Toledo Medical Center, 3000 Arlington Avenue, Toledo, OH 43614, USA

Abstract

Introduction: Breast cancer is the second most common cancer among women in the United States. Metaplastic breast cancer is characterized by two or more poorly differentiated cellular types, with epithelial or mesenchymal components. Metaplastic breast carcinoma is a rare and aggressive entity, accounting for less than 1% of invasive breast cancers. Hence, there is insignificant literature and research. Few cases are described in the literature. We report a rare case of metaplastic breast carcinoma with squamous and spindle cell differentiation. Case Report: An 82-year-old female was diagnosed with metaplastic breast cancer with squamous and spindled differentiation based on histological appearance. She underwent mastectomy, and we track her radiation follow-up. Conclusion: The report reviews and corroborates existing literature regarding clinical features, histologic characteristics, and treatment methods, and explores genetic components and clinical trials underway.

Publisher

Edorium Journals Pvt. Ltd.

Subject

Physical Therapy, Sports Therapy and Rehabilitation,Earth-Surface Processes,Plant Science,Ecology,Ecology, Evolution, Behavior and Systematics,Forestry,General Medicine,General Engineering,Electrical and Electronic Engineering,Hardware and Architecture,Software,Electrical and Electronic Engineering,Instrumentation,Electrical and Electronic Engineering,Computational Theory and Mathematics,Theoretical Computer Science,General Earth and Planetary Sciences,General Environmental Science,Hematology

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