Evaluation of Anti-Allergic Property of MulminaTM Mango Juice in In Vivo Models-Reference-Cited by-同舟云学术

Evaluation of Anti-Allergic Property of MulminaTM Mango Juice in In Vivo Models

Published:2024-09-04 Issue:2 Volume:22 Page:96-103
ISSN:1304-7582
Container-title:Akademik Gıda
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Author:

Nandeesh Rudrappa¹^ORCID,Jagdala Rajesh N.²^ORCID,Kumar Bs Ashok³^ORCID,A Mouna⁴^ORCID,Chuplinkar Sunil S.⁵^ORCID,E. Manjunatha¹^ORCID,Veerapur Veeresh P.¹^ORCID

Affiliation:

1. Department of Pharmacognosy, Sree Siddaganga College of Pharmacy

2. Jagadale Industries Pvt Ltd. Bangalore

3. Department of Pharmacognosy, RL Jalappa College of Pharmacy, Sri Devaraj Urs Academy of Higher Education and Research (SDUAHER)

4. Department of Pharmaceutics, Shridevi College of Pharmacy

5. Research Scholar, JSS Academy of Higher Education & Research (JSSAHER)

Abstract

MulminaTM mango juice is the brand name of the formulation containing Mangifera indica L., Centella asiatica, Curcuma longa, essential vitamins and minerals. MulminaTM is natural immune booster and stress reliever. The present study is to investigate the effect of MulminaTM mango juice for its anti-allergic property by in vivo models like: Compound 48/80 induced mast cell degranulation in rat mesentery, rat peritoneal fluid, milk induced leucocytosis and eosinophilia in mice and systemic anaphylaxis in mice. MulminaTM mango juice exhibited potential anti-allergic property with marked reduction in number of degranulated cells, reduction in antigen (milk) induced immunological reaction by lowering leucocytes and eosinophil count and showed protection against histamine induced anaphylactic shock. These results constitute the first report of the anti-allergic properties of MulminaTM mango juice on allergic models, as well as suggesting that this natural fruit juice could be successfully used in the allergic conditions.

Publisher

Akademik Gida

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