Density-constrained Chemotaxis and Hele-Shaw flow

Author:

Kim Inwon,Mellet Antoine,Wu Yijing

Abstract

We consider a model of congestion dynamics with chemotaxis, where the density of cells follows the chemical signal it generates, while observing an incompressibility constraint (incompressible parabolic-elliptic Patlak-Keller-Segel model). We show that when the chemical diffuses slowly and attracts the cells strongly, then the dynamics of the congested cells is well approximated by a surface-tension driven free boundary problem. More precisely, we rigorously establish the convergence of the solution to the characteristic function of a set whose evolution is determined by the classical Hele-Shaw free boundary problem with surface tension.

The problem is set in a bounded domain, which leads to an interesting analysis on the limiting boundary conditions. Namely, we prove that the assumption of Robin boundary conditions for the chemical potential leads to a contact angle condition for the free interface (in particular Neumann boundary conditions lead to an orthogonal contact angle condition, while Dirichlet boundary conditions lead to a tangential contact angle condition).

Funder

National Science Foundation

Publisher

American Mathematical Society (AMS)

Subject

Applied Mathematics,General Mathematics

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