We discuss several kinds of Willmore surfaces of flat normal bundle in this paper. First we show that every S-Willmore surface with flat normal bundle in
S
n
S^n
must be located in some
S
3
⊂
S
n
S^3\subset S^n
, from which we characterize the Clifford torus as the only non-equatorial homogeneous minimal surface in
S
n
S^n
with flat normal bundle, which improves a result of K. Yang. Then we derive that every Willmore two sphere with flat normal bundle in
S
n
S^n
is conformal to a minimal surface with embedded planer ends in
R
3
\mathbb {R}^3
. We also point out that for a class of Willmore tori, they have a flat normal bundle if and only if they are located in some
S
3
S^3
. In the end, we show that a Willmore surface with flat normal bundle must locate in some
S
6
S^6
.