This article considers the computational (acoustic) wave propagation in strongly heterogeneous structures beyond the assumption of periodicity. A high contrast between the constituents of microstructured multiphase materials can lead to unusual wave scattering and absorption, which are interesting and relevant from a physical viewpoint, for instance, in the case of crystals with defects. We present a computational multiscale method in the spirit of the Localized Orthogonal Decomposition and provide its rigorous a priori error analysis for two-phase diffusion coefficients that vary between
1
1
and very small values. Special attention is paid to the extreme regimes of high frequency, high contrast, and their previously unexplored coexistence. A series of numerical experiments confirms the theoretical results and demonstrates the ability of the multiscale approach to efficiently capture relevant physical phenomena.