4-Aminoantipyrine-new organotin complexes, synthesis, structure and antioxidant activity

Abstract

ABSTRACT. 4-Aminoantipyrine was used as ligand to prepare new complexes of triphenyltin, di-butyl and dimethyl-tin complexes by condensation reaction with the corresponding organotin chloride salts. The complexes were identified by different techniques, such as infrared spectra, (tin and proton) magnetic resonance and elemental analyses. The antioxidant activity of 4-aminoantipyrine and prepared complexes were studied by two different methods; Free radical scavenging activity DPPH and CUPRRAC methods. Tri and di-tin complexes gave high percentage inhibition than ligand with both methods due to tin moiety, also triphenyltin carboxylate complex was the best compared with the others.   KEY WORDS: 4-Aminoantipyrine, Condensation, Triphenyl tin chloride, DPPH and CUPRRAC methods Bull. Chem. Soc. Ethiop. 2023, 37(5), 1163-1170.                                                          DOI: https://dx.doi.org/10.4314/bcse.v37i5.9