Effect of combination of intravenous general anesthesia with propofol and fentanyl on surgery for aortic dissection repair in patients, and its influence on respiratory and circulatory functions

Abstract

Purpose: To investigate the effect of application of propofol in combination with fentanyl intravenous anesthesia in interventional surgery for aortic dissection repair, and its influence on respiratory and circulatory functions in patients.Methods: 100 patients undergoing interventional surgery for aortic dissection repair in Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang. China from  ovember 2018 to May 2020 were assigned equally to control group (CG) and study group (SG). CG received general anesthesia with propofol, while those in SG received combined intravenous general anesthesia with propofol and fentanyl. Time of anesthesia onset, postoperative awakening time, extubation time, respiratory function indicators and circulatory function indicators before operation (T0), and at intraoperative 1 h (T1), intraoperative 2 h (T2) and postoperative 2 h (T3); as well as postoperative VAS pain scores, and Ramsay sedation scores were determined and compared.Results: Compared with CG, SG had shorter anesthesia onset, shorter postoperative awakening and extubation times, and lower postoperative VAS pain and Ramsay sedation scores (p < 0.05). At T1, T2 and T3, indicators of respiratory and circulatory functions were better in SG than in CG (p > 0.05).Conclusion: Combined intravenous general anesthesia using propofol and fentanyl was more effective in interventional surgery for repair of aortic dissection, and it enhanced respiratory and circulatory functions in the patients.