Effects of flavonoids on vascular activity

Abstract

Flavonoids, encompassing various polyphenolic compounds found in plants, exert significant effects on vascular function. Particularly notable is their role in inducing vasodilation, a process crucial for regulating blood pressure (BP) and enhancing cardiovascular health. Through their vasodilatory properties, flavonoids contribute to improved blood flow and endothelial function. In addition, flavonoids demonstrate antiplatelet effects, which play a vital role in preventing abnormal blood clot formation and reducing the risk of thrombotic events. By inhibiting platelet aggregation, flavonoids help maintain vascular integrity and mitigate the likelihood of cardiovascular complications. In addition to vasodilation and antiplatelet effects, flavonoids exhibit potential benefits in managing hypertension. Studies suggest that flavonoids can help regulate BP by promoting vasorelaxation and modulating endothelial function. These mechanisms contribute to the overall maintenance of cardiovascular homeostasis and may offer therapeutic avenues for hypertension management. This review aims to comprehensively explore the multifaceted effects of flavonoids on vascular function, with an emphasis on their vasodilatory properties, antiplatelet effects, and potential implications for hypertension management within the existing literature.