Synthesis and Algicidal Activity of (+)-Cyanobacterin and Its Stereoisomer

Author:

ISHIBASHI Fumito1,PARK Suhwan1,KUSANO Takako1,KUWANO Kazuyoshi2

Affiliation:

1. Faculty of Fisheries, Nagasaki University

2. Graduate School of Science and Technology, Nagasaki University

Publisher

Oxford University Press (OUP)

Subject

Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology

Reference21 articles.

1. 1) Mason, C. P., Edwards, K. R., Carlson, R. E., Pignatello, J., Gleason, F. K., and Wood, J. M., Isolation of chlorine-containing antibiotic from the freshwater cyanobacterium Scytonema hofmanni. Science, 215, 400–402 (1982).

2. 2) Pignatello, J. J., Porwoll, J., Carlson, R. E., Xavier, A., Gleason, F. K., and Wood, J. M., Structure of the antibiotic cyanobacterin, a chlorine-containing γ-lactone from the freshwater cyanobacterium Scytonema hofmanni. J. Org. Chem., 48, 4035–4043 (1983).

3. 3) Jong, T.T., Williard, P. G., and Porwoll, J. P., Total synthesis and X-ray structure determination of cyanobacterin. J. Org. Chem., 49, 735–736 (1984).

4. 4) Gleason, F. K., and Porwoll, J., X-ray structure determination of the naturally occurring isomer of cyanobacterin. J. Org. Chem., 51, 1615–1616 (1986).

5. 5) Gleason, F. K., and Paulson, J. L., Site of action of the natural algicide, cyanobacterin in the blue-green alga, Synechococcus sp. Arch. Microbiol., 138, 273–277 (1984).

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