3. Pharmacokinetic Analysis of Organ-Organ Interaction in Microphysiological System/Organs-on-a-chip
Author:
Affiliation:
1. Department of Molecular Pharmacotherapeutics, Faculty of Pharmacy, Kanazawa University
Publisher
Japanese Society of Clinical Pharmacology and Therapeutics
Subject
Pharmacology (medical),Pharmacology
Link
https://www.jstage.jst.go.jp/article/jscpt/51/3/51_174/_pdf
Reference14 articles.
1. 1) Rodighiero V. Effects of liver disease on pharmacokinetics. An update. Clin Pharmacokinet. 1999; 37 (5) : 399-431. doi: 10.2165/00003088-199937050-00004.
2. 2) Shibata SI, Chung V, Synold TW, Longmate JA, Suttle AB, Ottesen LH, et al. Phase I study of pazopanib in patients with advanced solid tumors and hepatic dysfunction: a national cancer institute organ dysfunction working group study. Clin Cancer Res. 2013; 19 (13) : 3631-9. doi: 10.1158/1078-0432.CCR-12-3214.
3. 3) Furuse J, Ishii H, Nakachi K, Suzuki E, Shimizu S, Nakajima K. Phase I study of sorafenib in Japanese patients with hepatocellular carcinoma. Cancer Sci. 2008; 99 (1) : 159-65. doi: 10.1111/j.1349-7006.2007.00648.x.
4. 4) van Giersbergen PLM, Popescu G, Bodin F, Dingemanse J. Influence of mild liver impairment on the pharmacokinetics and metabolism of bosentan, a dual endothelin receptor antagonist. J Clin Pharmacol. 2003; 43 (1) : 15-22. doi: 10.1177/0091270002239701.
5. 5) Kawanishi T, Arakawa H, Masuo Y, Nakamichi N, Kato Y. Bile duct obstruction leads to increased intestinal expression of breast cancer resistance protein with reduced gastrointestinal absorption of imatinib. J Pharm Sci. 2019; 108 (9) : 3130-7. doi: 10.1016/j.xphs.2019.05.017.
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