Disarming pathogens: benefits and challenges of antimicrobials that target bacterial virulence instead of growth and viability
Author:
Affiliation:
1. Institute of Health & Biomedical Innovation, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD 4059, Australia
Publisher
Future Science Ltd
Subject
Drug Discovery,Pharmacology,Molecular Medicine
Link
http://www.future-science.com/doi/pdf/10.4155/fmc-2016-0227
Reference20 articles.
1. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study
2. World Health Organization. Antimicrobial Resistance: Global Report on Surveillance (2014). www.who.int/drugresistance/documents/surveillancereport/en/.
3. The Review on Antimicrobial Resistance, Chaired by Jim O'Neill. Antimicrobial Resistance: Tackling a Crisis for the Health and Wealth of Nations. HM Government and Wellcome Trust, UK (2014). https://amr-review.org/sites/default/files/AMR%20Review%20Paper%20-%20Tackling%20a%20crisis%20for%20the%20health%20and%20wealth%20of%20nations_1.pdf.
4. Alternatives to antibiotics—a pipeline portfolio review
5. Targeting virulence: can we make evolution-proof drugs?
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