Disarming pathogens: benefits and challenges of antimicrobials that target bacterial virulence instead of growth and viability

Author:

Totsika Makrina1

Affiliation:

1. Institute of Health & Biomedical Innovation, School of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD 4059, Australia

Publisher

Future Science Ltd

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Reference20 articles.

1. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study

2. World Health Organization. Antimicrobial Resistance: Global Report on Surveillance (2014). www.who.int/drugresistance/documents/surveillancereport/en/.

3. The Review on Antimicrobial Resistance, Chaired by Jim O'Neill. Antimicrobial Resistance: Tackling a Crisis for the Health and Wealth of Nations. HM Government and Wellcome Trust, UK (2014). https://amr-review.org/sites/default/files/AMR%20Review%20Paper%20-%20Tackling%20a%20crisis%20for%20the%20health%20and%20wealth%20of%20nations_1.pdf.

4. Alternatives to antibiotics—a pipeline portfolio review

5. Targeting virulence: can we make evolution-proof drugs?

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