Recent developments in microfluidic chip-based separation devices coupled to MS for bioanalysis-Reference-Cited by-同舟云学术

Recent developments in microfluidic chip-based separation devices coupled to MS for bioanalysis

Published:2013-10 Issue:20 Volume:5 Page:2567-2580
ISSN:1757-6180
Container-title:Bioanalysis
language:en
Short-container-title:Bioanalysis

Author:

Lin Shu-Ling¹,Lin Tzuen-Yeuan¹,Fuh Ming-Ren²

Affiliation:

1. Department of Chemistry, Soochow University, No. 70, Linhsi Road, Shihlin, 11102 Taipei, Taiwan

2. Department of Chemistry, Soochow University, No. 70, Linhsi Road, Shihlin, 11102 Taipei, Taiwan.

Abstract

In recent years, the development of microfluidic chip separation devices coupled to MS has dramatically increased for high-throughput bioanalysis. In this review, advances in different types of microfluidic chip separation devices, such as electrophoresis- and LC-based microchips, as well as 2D design of microfluidic chip-based separation devices will be discussed. In addition, the utilization of chip-based separation devices coupled to MS for analyzing peptides/proteins, glycans, drug metabolites and biomarkers for various bioanalytical applications will be evaluated.

Publisher

Future Science Ltd

Subject

Medical Laboratory Technology,Clinical Biochemistry,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Analytical Chemistry

Link

http://www.future-science.com/doi/pdf/10.4155/bio.13.196

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