Matrix interference in ligand-binding assays: challenge or solution?-Reference-Cited by-同舟云学术

Matrix interference in ligand-binding assays: challenge or solution?

Published:2014-04 Issue:8 Volume:6 Page:1029-1031
ISSN:1757-6180
Container-title:Bioanalysis
language:en
Short-container-title:Bioanalysis

Author:

DeSilva Binodh¹,Garofolo Fabio²

Affiliation:

1. Bristol Myers Squibb, Route 206 & Provinceline Road, Princeton, NJ 08543, USA

2. Algorithme Pharma Inc., 575 Armand-Frappier, Laval, Quebec, H7V 4B3, Canada

Publisher

Future Science Ltd

Subject

Medical Laboratory Technology,Clinical Biochemistry,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Analytical Chemistry

Link

http://www.future-science.com/doi/pdf/10.4155/bio.14.92

Reference16 articles.

1. Critical ligand binding reagent preparation/selection: When specificity depends on reagents

2. Recommendations for the Bioanalytical Method Validation of Ligand-Binding Assays to Support Pharmacokinetic Assessments of Macromolecules

3. KelleyM, DeSilva B. Analytical considerations for immunoassays for macromolecules. In:Handbook of Pharmaceutical Biotechnology.Cox Gad S (Ed.). Wiley-InterScience, John Wiley & Sons Inc., Hoboken, NJ, USA (2007).

4. Protein-based matrix interferences in ligand-binding assays

5. Evaluating the impact of matrix effects on biomarker assay sensitivity

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