Challenges of probe cocktail approach for human drug–drug interaction assays-Reference-Cited by-同舟云学术

Challenges of probe cocktail approach for human drug–drug interaction assays

Published:2018-12 Issue:24 Volume:10 Page:1969-1972
ISSN:1757-6180
Container-title:Bioanalysis
language:en
Short-container-title:Bioanalysis

Author:

Carrão Daniel B¹,de Oliveira Anderson RM¹,Magalhães Igor RS²

Affiliation:

1. Laboratório de Metabolismo In Vitro e Técnicas de Separação, Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo (FFCLRP-USP), 14040-901, Ribeirão Preto, Brazil

2. Núcleo de Estudos em Farmacocinética, Faculdade de Ciências Farmacêuticas, Universidade Federal do Amazonas (FCF-UFAM), 69077-000, Manaus, Brazil

Publisher

Future Science Ltd

Subject

Medical Laboratory Technology,Clinical Biochemistry,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Analytical Chemistry

Link

http://www.future-science.com/doi/pdf/10.4155/bio-2018-0247

Reference21 articles.

1. US FDA. In vitrometabolism- and transporter-mediated drug–drug interaction studies – guidance for industry. 1–47 (2017). https://www.fda.gov/downloads/Drugs/Guidances/UCM581965.pdf.

2. Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5′-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography–Tandem Mass Spectrometry

3. An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposure

4. An improved substrate cocktail for assessing direct inhibition and time-dependent inhibition of multiple cytochrome P450s

5. HPLC–high-resolution mass spectrometry with polarity switching for increasing throughput of human in vitro cocktail drug–drug interaction assay

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