Considerations in the design of clinical and epidemiological metabolic phenotyping studies

Author:

Theodoridis Georgios1,Gika Helen G2,Nicholls Andrew3,Wilson Ian D4

Affiliation:

1. Georgios Theodoridis is an Associate Professor of Analytical Chemistry at the Aristotle University of Thessaloniki (Greece). His research aims to develop and validate analytical methods in bioanalysis, drug metabolism/pharmacokinetics and biomarker discovery. He has more than 100 publications in peer-reviewed journals and 15 book chapters.

2. Helen G Gika is a Lecturer of Biomolecular Analysis at the Aristotle University of Thessaloniki. Her research focuses on analytical separations (HPLC, LC–MS and GC–MS) and their application in life sciences. Her work has resulted in more than 30 publications and eight book chapters.

3. Andrew Nicholls obtained his PhD from the University of London (UK) in analytical and theoretical chemistry as applied to drug metabolism and toxicology. Following studies as a senior postdoctoral fellow with Merck, Sharpe and Dohme (Harlow, UK), and work as an Associate Director for Metabometrix Ltd (London, UK), he joined GlaxoSmithKline (Ware, UK), where he now heads the Biochemistry and Cellular Pathology/Toxicology groups in the investigative arm of Safety Assessment. His principal areas of research...

4. Ian D Wilson trained as a biochemist at the University of Manchester Institute of Science and Technology (UK), going on to a PhD at Keele University (UK) on insect moulting hormones. He has worked in the pharmaceutical industry, most recently as a Senior Principal Scientist in the Department of Drug Metabolism and Pharmacokinetics at the AstraZeneca Research site at Alderley Park in Cheshire (UK). Since 2012, he has been at Imperial College in London (UK), where he has a personal Chair in drug metabolism...

Publisher

Future Science Ltd

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