1. Institute for Theoretical Medicine, Inc., 26-1 Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa, 251-0012, Japan
2. Department of Life Science Informatics & Data Science, B-IT, LIMES Program Unit Chemical Biology & Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Friedrich-Hirzebruch-Allee 5/6, D-53115, Bonn, Germany