Strategies for electrochemical detection in immunochemistry

Author:

Centi Sonia1,Laschi Serena1,Mascini Marco12

Affiliation:

1. Università degli Studi di Firenze, Dipartimento di Chimica, Polo Scientifico, via della Lastruccia 3, 50019 Sesto Fiorentino, Firenze, Italy

2. Instituto Nazionale Biostrutture e Biosistemi, Viale medaglie d’oro 305, 00136 Roma, Italy.

Abstract

In this review, the current status of research in electrochemical immunosensors is considered. We primarily focus on label-free and enzyme-labeled immunosensors, and the analytical capabilities of these devices are discussed. Moreover, the use of magnetic beads as new materials for immunosensors coupled with electrochemical sensing is also described, together with the application of new molecules such as aptamers as specific biorecognition elements. Examples of the applicability of these devices in solving various analytical problems in clinical, environmental and food fields are reported. Finally, the prospects for the further development of immunosensor technologies are shown.

Publisher

Future Science Ltd

Subject

Medical Laboratory Technology,Clinical Biochemistry,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Analytical Chemistry

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3. Establishment of a specific radioimmunoassay for bovine interferon τ

4. GoslingJP. Enzyme immunoassay. In:Immunoassay. Diamandis EP, Christopoulos TK (Eds). Academic Press, San Diego, CA, USA,287–308 (1996).

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