Analysis of small-molecule drugs in tissue: current practices

Author:

Tsefrikas Vikki1,Zhang Xin2

Affiliation:

1. Vikki Tsefrikas obtained her BS and MS degrees from Worcester Polytechnic Institute (MA, USA) in 2001 and 2002, respectively. She went on to earn a doctorate in organic chemistry in 2007 from Boston College (MA, USA). After nearly 2 years of postdoctoral work at Astra Zeneca at Waltham (MA, USA) she joined Agilux Labs and is currently a principal scientist in the discovery bioanalysis group. She has worked on many tissue analysis projects with her team gaining both an in-depth understanding and hands-on...

2. After Xin Zhang earned his PhD degree from the University of Iowa (USA), he spent 5 years at Northeastern University (MA, USA) conducting research on MS applications. He is currently a Senior Director at Agilux Labs overseeing operation of in vitro ADMET, in vivo pharmacokinetics and discovery bioanalysis groups. Before joining Agilux Labs, he also worked and held group leader and director positions in two other contract research organizations, Charles River Labs and Tandem Labs. His former and current...

Publisher

Future Science Ltd

Reference17 articles.

1. Dosimetry and preliminary human studies of 18F-5-fluorouracil

2. Methods determining phosphor imaging limits of quantitation in whole-body autoradiography rodent tissue distribution studies affect predictions of 14C human dosimetry

3. Mass Spectrometry for Drug Discovery and Drug Development. Wiley Series on Mass Spectrometry (First Edition). Korfmarcher WA (Ed.). Wiley, NY, USA (2013) .

4. US FDA. Guidance for Industry: Bioanalytical Method Validation. US Department of Health and Human Service, US FDA Center for Drug Evaluation, MD, USA (2001) .

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