Interview with Dr Bowsher

Abstract

Dr Bowsher is currently a senior research advisor at AIT Biosciences advising on technical, regulatory and business development matters related to bioanalysis of biotherapeutics, as well as maintaining his consultancy and laboratory businesses at B2S Consulting® (IN, USA), and B2S Labs (IN, USA), respectively. Formerly working at EMD Millipore’s BioPharma Services for 10 years and at Lilly Research Laboratories for 30 years, Dr Bowsher brings more than 40 years of experience in the pharmaceutical/biotech and CRO industries. He received a bachelor’s degree in chemistry from Indiana University (IN, USA), and holds a master’s degree and doctorate in biochemistry from the Indiana University School of Medicine. He is an adjunct assistant professor of biochemistry and molecular biology at the Indiana University School of Medicine. Since 1980, he has published more than 100 research papers and monographs, and 105 abstracts, as well as holding three patents. In 2001, Dr Bowsher founded and organized the Ligand Binding Assay Bioanalytical Focus Group (LBABFG) within the American Association of Pharmaceutical Scientists (AAPS) and in 2004 he was elected as an AAPS Fellow, as well as being awarded an AAPS Presidential Citation for his work in establishing an educational program, and has served as the co-organizer for the past 6 years of the highly successful AAPS Immunogenicity Training Course. In 2012, Dr Bowsher received the Distinguished Alumnus Award, School of Science, Indiana University-Purdue University (IN, USA). In March 2013, Dr Bowsher spoke to Alexandra Sklan at Bioanalysis regarding his bioanalytical career, involvement in the AAPS and the future outlook relating to macromolecule bioanalysis. His primary research interests are the development and validation of ligand binding assays for the bioanalysis of macromolecules, endogenous compounds and conventional xenobiotic drugs to support regulatory-compliant assessments of PK/TK, PD and safety, and the ADME of biotherapeutics.