Immunogenicity for antisense oligonucleotides: a risk-based assessment
Author:
Affiliation:
1. Biogen, 225 Binney Street, Cambridge, MA 02142, USA
2. Immunologix Laboratories, 4710 Eisenhower Blvd, Building D, Tampa, FL 33634, USA
Publisher
Future Science Ltd
Subject
Medical Laboratory Technology,Clinical Biochemistry,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Analytical Chemistry
Link
https://www.future-science.com/doi/pdf/10.4155/bio-2019-0133
Reference20 articles.
1. Antisense Drug Technology
2. Antisense oligonucleotides: towards clinical trials
3. The Influence of Antisense Oligonucleotide-induced RNA Structure on Escherichia coli RNase H1 Activity
4. 2′-Carbohydrate modifications in antisense oligonucleotide therapy: importance of conformation, configuration and conjugation
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