Inception and Development of a LC–MS/MS Assay for the Multiplexed Quantitation of Nine Human Drug Transporter Biomarkers-Reference-Cited by-同舟云学术

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Inception and Development of a LC–MS/MS Assay for the Multiplexed Quantitation of Nine Human Drug Transporter Biomarkers

Published:2024-03 Issue:6 Volume:16 Page:347-362
ISSN:1757-6180
Container-title:Bioanalysis
language:en
Short-container-title:Bioanalysis

Author:

Kadar Eugene P¹^ORCID,Holliman Christopher L¹,Vourvahis Manoli²,Rodrigues A David³

Affiliation:

1. Bioanalytical Group, Medicine Design, Pfizer Worldwide Research & Development, Pfizer, Inc., 445 Eastern Point Road, Groton, CT06340, USA

2. Clinical Pharmacology, Pfizer Worldwide Research & Development, Pfizer, Inc., 66 Hudson Blvd. E, New York, NY10001, USA

3. Transporter Sciences Group, Medicine Design, Pfizer Worldwide Research & Development, Pfizer, Inc., 445 Eastern Point Road, Groton, CT06340, USA

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.4155/bio-2023-0197

Reference39 articles.

1. Reimagining the Framework Supporting the Static Analysis of Transporter Drug Interaction Risk; Integrated Use of Biomarkers to Generate Pan‐Transporter Inhibition Signatures

2. Drug–Drug Interaction Studies: Regulatory Guidance and An Industry Perspective

3. Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein‐Mediated Drug‐Drug Interactions in Healthy Volunteers

4. A novel hydrophilic interaction chromatography assay characterization of 4-pyridoxic acid, an emergent renal organic anion transporter 1/3 transporter biomarker

5. A Multiplexed HILIC-MS/HRMS Assay for the Assessment of Transporter Inhibition Biomarkers in Phase I Clinical Trials: Isobutyryl-Carnitine as an Organic Cation Transporter (OCT1) Biomarker

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Utility of Biomarker‐Informed Drug Interaction Evaluation in Drug Development and Regulatory Decision Making;Clinical Pharmacology & Therapeutics;2024-09-09

2. Innovative Approaches to Optimize Clinical Transporter Drug–Drug Interaction Studies;Pharmaceutics;2024-07-26

3. Expanding Role of Endogenous Biomarkers for Assessment of Transporter Activity in Drug Development: Current Applications and Future Horizon;Pharmaceutics;2024-06-25

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