Divergent de novo synthesis of 2,4,5-trideoxyhexopyranosides derivatives of podophyllotoxin as anticancer agents
Author:
Affiliation:
1. Institute of Special Environmental Medicine, Nantong University, Nantong 226001, PR China
2. School of Pharmacy, Nantong University, Nantong 226001, PR China
3. New Drug Research Center, China Pharmaceutical University, Nanjing 210009, PR China
Abstract
Publisher
Future Science Ltd
Subject
Drug Discovery,Pharmacology,Molecular Medicine
Link
https://www.future-science.com/doi/pdf/10.4155/fmc-2018-0593
Reference21 articles.
1. Podophyllotoxin derivatives as an excellent anticancer aspirant for future chemotherapy: A key current imminent needs
2. Synthesis and antitumor activity of novel aroylthiourea derivatives of podophyllotoxin
3. One-pot synthesis of podophyllotoxin–thiourea congeners by employing NH2SO3H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents
4. Etoposide: four decades of development of a topoisomerase II inhibitor
5. Synthesis and biological evaluation of new spin-labeled derivatives of podophyllotoxin
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