The impact of micelle size and increased absorption of ubiquinone using a novel delivery system (AquaCelle®)

Abstract

Aim: The objective of this study was to determine whether the use of a self-emulsifying drug delivery system AquaCelle®, could improve the absorption of CoQ10. Materials & methods: Fifty-seven healthy males and females completed this study with the primary outcome as change in plasma absorption of CoQ10 over a 10-h period. Results: All AquaCelle groups significantly increased CoQ10 concentrations up to three-times that of the standard CoQ10 supplement. Ubiquinone with AquaCelle achieved an equivalent absorption to ubiquinol. Conclusion: The novel delivery system AquaCelle demonstrates superior absorption for the supply of ubiquinone when compared with a standard ubiquinone extract. These results further indicate that ubiquinone with AquaCelle absorbs as effectively as the typically superior absorbing ubiquinol at the same 100 mg dose.