Application of emerging toxicity screens in drug discovery: challenges and implications-Reference-Cited by-同舟云学术

Application of emerging toxicity screens in drug discovery: challenges and implications

Published:2009-10 Issue:7 Volume:1 Page:1201-1205
ISSN:1756-8919
Container-title:Future Medicinal Chemistry
language:en
Short-container-title:Future Medicinal Chemistry

Author:

Wilson Alan GE¹,Liu Xuemei²,Kramer Jeffrey A²

Affiliation:

1. Vice President, Drug Metabolism, Pharmacokinetics, Toxicology and Pathology, Lexicon Pharmaceuticals Inc., 8800 Technology Forest Place, The Woodlands, TX 77381-1160, USA.

2. Drug Metabolism, Pharmacokinetics, Toxicology and Pathology, Lexicon Pharmaceuticals Inc., 8800 Technology Forest Place, The Woodlands, TX 77381, USA.

Publisher

Future Science Ltd

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Link

http://www.future-science.com/doi/pdf/10.4155/fmc.09.108

Reference42 articles.

1. Genetically Engineered Cell Lines: Characterisation and Applications in Toxicity Testing

2. In Vitro Toxicological Methods for Environmental Health Testing

3. Estimating The Cost Of New Drug Development: Is It Really $802 Million?

4. Data Mining and Machine Learning Techniques for the Identification of Mutagenicity Inducing Substructures and Structure Activity Relationships of Noncongeneric Compounds

5. Data Mining and Knowledge Discovery in Predictive Toxicology

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1. Predicting in vivo safety characteristics using physiochemical properties and in vitro assays;Future Medicinal Chemistry;2011-09

2. Chapter 1. Introduction and Overview;Drug Discovery;2011