Pharmacokinetic–pharmacodynamic reasoning in drug discovery and early development-Reference-Cited by-同舟云学术

Pharmacokinetic–pharmacodynamic reasoning in drug discovery and early development

Published:2009-11 Issue:8 Volume:1 Page:1371-1374
ISSN:1756-8919
Container-title:Future Medicinal Chemistry
language:en
Short-container-title:Future Medicinal Chemistry

Author:

Van Der Graaf Piet H¹,Gabrielsson Johan²

Affiliation:

1. Pharmacokinetics, Dynamics and Metabolism Department, Sandwich, Kent, UK.

2. AstraZeneca R&D Mölnda, Discovery DMPK & BAC CVGI, S-431 83 Mölndal, Sweden.

Publisher

Future Science Ltd

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Link

http://www.future-science.com/doi/pdf/10.4155/fmc.09.124

Reference28 articles.

1. GabrielssonJ, Weiner D.Pharmacokinetic & Pharmacodynamic Data Analysis – Concepts and Applications (Fourth Edition). Swedish Pharmaceutical Press, Stockholm, Sweden (2006).

2. Early integration of pharmacokinetic and dynamic reasoning is essential for optimal development of lead compounds: strategic considerations

3. Quantifying Biological Activity in Chemical Terms: A Pharmacology Primer To Describe Drug Effect

4. Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application tod-tubocurarine

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