Electromembrane extraction of peptides and amino acids – status and perspectives

Author:

Eie Linda Vårdal1,Rye Torstein Kige1,Hansen Frederik1,Halvorsen Trine Grønhaug1,Pedersen-Bjergaard Stig12

Affiliation:

1. Department of Pharmacy, University of Oslo, PO Box 1068 Blindern, 0316 Oslo, Norway

2. Department of Pharmacy, Faculty of Health & Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark

Abstract

This article reviews the scientific literature on electromembrane extraction (EME) of peptides and amino acids. In EME, target analytes are extracted from aqueous sample, through a supported liquid membrane (organic) and into a microliter volume of aqueous buffer (acceptor). Experimental conditions and performance for EME of peptides and amino acids are reviewed and discussed in detail, providing readers with an overview and basic understanding of the subject. In addition, this review discuss the potential for future applications, and scientific questions that need to be addressed for EME of peptides and amino acids to be generally accepted. EME is under commercialization, and therefore we expect it will be an active area of research in the near future.

Funder

Norges Forskningsråd

Publisher

Future Science Ltd

Subject

Medical Laboratory Technology,Clinical Biochemistry,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Analytical Chemistry

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