Recent advances in the application of antibodies as therapeutics-Reference-Cited by-同舟云学术

Recent advances in the application of antibodies as therapeutics

Published:2012-01 Issue:1 Volume:4 Page:73-86
ISSN:1756-8919
Container-title:Future Medicinal Chemistry
language:en
Short-container-title:Future Medicinal Chemistry

Author:

Burden Roberta E¹,Caswell Jill¹,Fay Francois¹,Scott Christopher J

Affiliation:

1. Molecular Therapeutics, School of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK

Abstract

The application of antibodies as therapeutic agents in the treatment of cancer now represents a significant proportion of the oncology drug arena. Despite this success, the ability to engineer and exploit antibodies in many different formats is ensuring that new avenues for their therapeutic application are constantly being examined. This review examines a selection of novel antibody-based therapeutic strategies that are currently in late preclinical and clinical evaluation.

Publisher

Future Science Ltd

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Link

http://www.future-science.com/doi/pdf/10.4155/fmc.11.165

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