What has polar surface area ever done for drug discovery?
Author:
Affiliation:
1. Argenta, 8/9 Spire Green Centre, Flex Meadow, Harlow, Essex, CM19 5TR, UK.
Abstract
Publisher
Future Science Ltd
Subject
Drug Discovery,Pharmacology,Molecular Medicine
Link
http://www.future-science.com/doi/pdf/10.4155/fmc.11.1
Reference38 articles.
1. MezeyPG. Molecular surfaces. In:Reviews in Computational Chemistry Vol. 1. Boyd DB, Lipkowitz KB (Eds). Wiley-VCH, NY, USA,265–294 (1990).
2. ErtlP. Polar surface area. In:Molecular Drug Properties: Methods and Prediction (Methods and Principles in Medicinal Chemistry, Vol. 37). Mannhold R (Ed.). Wiley-VCH, Weinheim, Germany,111–126 (2008).
3. ArturssonP, Bergström CAS. Intestinal absorption: the role of polar surface area. In:Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability (Methods and Principles in Medicinal Chemistry, Vol. 18). Van de Waterbeemd H, Lennernäs H, Artursson P (Eds). Wiley-VCH, Weinheim, Germany,341–357 (2003).
4. Electronic and structural features of γ-aminobutyric acid (GABA) and four of its direct agonists
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