Evaluation of cAMS for 14C microtracer ADME studies: opportunities to change the current drug development paradigm
Author:
Affiliation:
1. Novartis Pharma AG, Novartis Institutes for Biomedical Research, PK Sciences, Fabrikstrasse 14, CH-4002 Basel, Switzerland
2. Ionplus AG, Dietikon, Switzerland
3. Eidgenössische Technische Hochschule Zürich, Department Physik, Zürich, Switzerland
Abstract
Publisher
Future Science Ltd
Subject
Medical Laboratory Technology,Clinical Biochemistry,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Analytical Chemistry
Link
http://www.future-science.com/doi/pdf/10.4155/bio-2017-0216
Reference38 articles.
1. A rapid method for quantitatively estimating metabolites in human plasma in the absence of synthetic standards using a combination of liquid chromatography/mass spectrometry and radiometric detection
2. Determination of Exposure Multiples of Human Metabolites for MIST Assessment in Preclinical Safety Species without Using Reference Standards or Radiolabeled Compounds
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