Dexamethasone intravitreal implant (OZURDEX®) for macular edema secondary to noninfectious uveitis: a review of the literature

Author:

Massa Horace1,Georgoudis Panagiotis2,Panos Georgios D2ORCID

Affiliation:

1. Department of Ophthalmology, Geneva University Hospitals & Faculty of Medicine, University of Geneva, Geneva, CH-1205, Switzerland

2. Eye Treatment Centre, Whipps Cross University Hospital, Barts Health NHS Trust, London, E11 1NR, UK

Abstract

Macular edema (ME) is the leading cause of visual loss in uveitis and may persist long after ocular inflammation has been resolved. Local steroids are the first line treatment for uveitis and uveitic ME. Dexamethasone intravitreal implant (OZURDEX®; Allergan, Inc., CA, USA) has been used to treat diabetic ME and ME secondary to retinal vein occlusion. Recent studies have also demonstrated that Ozurdex may be effective treatment for patients with persistent uveitic ME. In this review, we present the results of the real word studies concerning the efficacy and safety of Ozurdex for the treatment of uveitic ME.

Publisher

Future Science Ltd

Subject

Pharmaceutical Science

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