Phase I and beyond – the importance of switching to patient’s plasma: considerations and perspectives on bioanalytical procedures

Author:

Srinivas Nuggehally R1,Mullangi Ramesh2

Affiliation:

1. Suramus Biopharm, J.P. Nagar, I Phase, Bangalore 560078, India.

2. Drug Metabolism & Pharmacokinetics, Jubilant Biosys Ltd, Bangalore, India

Publisher

Future Science Ltd

Subject

Medical Laboratory Technology,Clinical Biochemistry,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Analytical Chemistry

Reference20 articles.

1. Changing need for bioanalysis during drug development

2. Strategies for Improving the Quantitative Bioanalytical Performance of LC-MS in Pharmacokinetic Studies

3. SrinivasNR, Yao M. Bioanalytical considerations in present-day drug development: case study of bioanalysis of halofantrine with an update on its clinical pharmacology, metabolism, transport and distribution attributes. In:Drug Development Perspectives: Considerations, Challenges and Strategies. Srinivas NR (Ed.). HNB Publishing, NY, USA (2010).

4. Impact of disease on interferences in blood bioanalysis

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