Author:
Petríková Z. Adamcová,Kenderessy P. Kenderessy,Petrík O. Petrík,Adamec T. Adamec
Abstract
Anaesthetics and their influence on children’s brains have become one of the most discussed problems in paediatric anaesthesiology. The experimental studies on animal models have shown that the anaesthetics used in general anaesthesia should have an influence on neurodegenerative processes, neuroapoptosis and the unregulated death of the neuronal cells in the developing brain. Due to this reality, scientists are trying to discover how to minimize the adverse effects of anaesthesia and revise other alternatives of prevention anaesthesia-induced maladaptive behavioural disorders, especially in children.
The paper will present the procedures of preoperative management at a children’s faculty hospital in Banská Bystrica, Slovakia, our working place, and reveal how to minimize the adverse effects of anesthesia presenting in maladaptive behavioural disorders.
Reference10 articles.
1. Deshui Y., Linji Li, Neonatal anesthetic neurotoxicity: Insight into molecular mechanism of long- term neurocognitive deficits, Biomedicine and Pharmacotherapy, 2017, p.: 196-199. https://doi.org/10.1016/j.biopha.2016.12.062
2. Mason K.P., Paediatric emergence delirium: a comprehensive review and interpretation of the literature, British Journal of Anaesthesia, 2017, Oxford University Press, p. 335-343. https://doi.org/10.1093/bja/aew477
3. Moore Keith L., Persaud T.V.N., The Developing Human: Clinically Oriented Embryology, ISV nakladatelství, 1. Edition, 2002, ISBN: 80-85866-94-3
4. Kamat P.P., Kudchadkar S.R., The Journal of Pediatrics, 2018, p: 285-290. https://doi.org/10.1016/j.jpeds.2018.08.039
5. Malarbi S., Stragatt R., Characterizing the behaviour of children emerging with delirium from general anesthesia, Pediatric Anesthesia, 2011, p.942-950. https://doi.org/10.1111/j.1460-9592.2011.03646.x