Affiliation:
1. Russian Medical Academy of Continuous Professional Education (Moscow, Russia)
Abstract
The article presents a critical analysis of antibiotic usage tactics in the treatment of patients with COVID-19 existing in Russian and foreign healthcare, and discusses the possible causes of unjustified antibiotic aggression in this category of patients. The potential negative consequences of the widespread use of antibiotics in patients carrying a new coronavirus infection are analyzed: life-threatening cardiotoxicity in patients with the simultaneous administration of such a «popular» candidate etiologic therapy as a combination of azithromycin and hydroxychloroquine, the potential development of other serious adverse drug reactions (in particular, the development of an antibiotic-associated pseudomembranous colitis, etc.), the expected dramatic increase in the secondary drug resistance of potentially pathogenic microorganisms to widely and often prescribed antibiotics.
Publisher
Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy
Reference67 articles.
1. Zhou F., Yu T., Du R., Fan G., Liu Y., Liuet Z., et al. Clinical course, and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;28:395(10229):1054-1062. DOI: 10.1016/S0140-6736(20)30566-3
2. Ruan Q., Yang K., Wang W., Jiang L., Song J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive Care Med. 2020;46:846-848. DOI: 10.1007/s00134-020-05991-x
3. Ahmed S., Jafri L., Hoodbhoy Z., Siddiqui I. Prognostic value of serum procalcitonin in COVID-19 patients: a systematic review. 2021;25(1):77-84. DOI: 10.5005/jpjournals-10071-23706
4. COVID-19 rapid guideline: antibiotics for pneumonia in adults in hospital. NICE guideline. Published: 1 May 2020. Available at: www.nice.org.uk/guidance/ng173. Accessed March, 2021.
5. Borges do Nascimento I.J., Cacic N., Abdulazeem H.M., Caspar von Groote T., Jayarajah U., Weerasekaraet I., et al. Novel Coronavirus infection (COVID-19) in humans: a scoping review and meta-analysis. J Clin Med. 2020;9:941. DOI: 10.3390/jcm9040941
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