Pseudomonas aeruginosa: the history of one of the most successful nosocomial pathogens in Russian hospitals

Author:

Skleenova E.Yu1ORCID,Azizov I.S.1,Shek Е.А.1ORCID,Edelstein M.V.1ORCID,Kozlov R.S.1ORCID,Dekhnich A.V.1ORCID

Affiliation:

1. Institute of Antimicrobial Chemotherapy, Smolensk State Medical University

Abstract

Pseudomonas aeruginosa is recognized as one of the six most important pathogens in terms of antimicrobial resistance («ESKAPE» pathogens), and included by WHO in the group of microorganisms for which the need for development of new antimicrobial agents is crucial. In 2015, P. aeruginosa was the second (after Klebsiella spp.) most common nosocomial bacterial pathogen in Russia with the following resistance rates: amikacin – 45.2%, imipenem – 51.5%, meropenem – 53.3%, colistin – 2.2%, piperacillin/tazobactam – 61.4%, ceftazidime – 56.8%, ciprofloxacin – 61.2%. The majority of carbapenemase-producing isolates in Russia belong to the two epidemic lineages – CC235 and CC654.

Publisher

Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy

Subject

Pharmacology (medical),Infectious Diseases,Microbiology (medical),Epidemiology

Reference20 articles.

1. Rice L.B. Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE. J Infect Dis. 2008;197(8):10791081.

2. Reshedko G.K., Ryabkova E.L., Farashchuk A.N., Stratchounski L.S., and ROSNET study group. Non-Fermenting GramNegative Nosocomial Pathogens in Russian ICUs: Antimicrobial Resistance Problems. Klinicheskaja mikrobiologija i antimikrobnaja himioterapija. 2006;8:243-259. Russian.

3. Reshedko G.K., Ryabkova E.L., Kretchikova O.I., et al. Antimicrobial Resistance Patterns of Gram-negative Nosocomial Pathogens in Russian ICUs. Klinicheskaja mikrobiologija i antimikrobnaja himioterapija. 2008;10:96-112. Russian.

4. Skleenova E., Sukhorukova M., Timokhova A., et al. Sharp increase in carbapenem-non-susceptibility and carbapenemase production rates in nosocomial Gram-negative bacteria in Russia over the last decade. 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), 2012, Denver, CO, USA. Abstract C21092.

5. Edelstein M.V., Skleenova E.Yu., Shevchenko O.V., et al. Prevalence and Molecular Epidemiology of Gram-negative Bacteria Producing Metallo-b-lactamases (MBLs) in Russia, Belarus and Kazakhstan. Klinicheskaja mikrobiologija i antimikrobnaja himioterapija. 2012;14:132-152. Russian.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3