Design and Implementation of a Randomized Crossover Study of Valproic Acid and Antiretroviral Therapy to Reduce the HIV Reservoir-Reference-Cited by-同舟云学术

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Design and Implementation of a Randomized Crossover Study of Valproic Acid and Antiretroviral Therapy to Reduce the HIV Reservoir

Published:2012-12 Issue:6 Volume:13 Page:301-307
ISSN:1528-4336
Container-title:HIV Clinical Trials
language:en
Short-container-title:HIV Clinical Trials

Author:

Routy J. P.,Angel J. B.,Spaans J. N.,Trottier B.,Rouleau D.,Baril J. G.,Harris M.,Trottier S.,Singer J.,Chomont N.,Sékaly R. P.,Tremblay C. L.

Publisher

Informa UK Limited

Subject

Pharmacology (medical),Infectious Diseases

Link

http://www.tandfonline.com/doi/pdf/10.1310/hct1306-301

Reference25 articles.

1. Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

2. Identification of a Reservoir for HIV-1 in Patients on Highly Active Antiretroviral Therapy

3. Early establishment of a pool of latently infected, resting CD4+ T cells during primary HIV-1 infection

4. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

5. Histone acetyltransferases regulate HIV-1 enhancer activity in vitro

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