Europe’s first and last field trial of gene-edited plants?

Author:

Faure Jean-Denis1,Napier Johnathan A2ORCID

Affiliation:

1. Institut Jean-Pierre Bourgin, INRA, AgroParisTech, CNRS, Université Paris-Saclay, Versailles, France

2. Department of Plant Sciences, Rothamsted Research, Harpenden, United Kingdom

Abstract

On 5 June this year the first field trial of a CRISPR-Cas-9 gene-edited crop began at Rothamsted Research in the UK, having been approved by the UK Department for Environment, Food & Rural Affairs. However, in late July 2018, after the trial had started, the European Court of Justice ruled that techniques such as gene editing fall within the European Union’s 2001 GMO directive, meaning that our gene-edited Camelina plants should be considered as genetically modified (GM). Here we describe our experience of running this trial and the legal transformation of our plants. We also consider the future of European plant research using gene-editing techniques, which now fall under the burden of GM regulation, and how this will likely impede translation of publicly funded basic research.

Funder

Association Instituts Carnot

AgroParisTech

Institut National de la Recherche Agronomique

Biotechnology and Biological Sciences Research Council

Publisher

eLife Sciences Publications, Ltd

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Reference15 articles.

1. Advice on genome-edited Camelina plants with increased levels of oleic acid;ACRE,2018

2. Opinion of Advocate General Bobek delivered on 18 January 2018;Bobek,2018

3. The first crop plant genetically engineered to release an insect pheromone for defence;Bruce;Scientific Reports,2015

4. Consent letter;DEFRA,2018

5. Camelina;Guy,2008

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