Pre-stimulus phase and amplitude regulation of phase-locked responses are maximized in the critical state

Author:

Avramiea Arthur-Ervin1ORCID,Hardstone Richard12ORCID,Lueckmann Jan-Matthis13ORCID,Bím Jan14ORCID,Mansvelder Huibert D1ORCID,Linkenkaer-Hansen Klaus1ORCID

Affiliation:

1. Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research (CNCR), Amsterdam Neuroscience, Amsterdam, Netherlands

2. Neuroscience Institute, New York University School of Medicine, New York, United States

3. Technical University of Munich, Munich, Germany

4. Czech Technical University in Prague, Prague, Czech Republic

Abstract

Understanding why identical stimuli give differing neuronal responses and percepts is a central challenge in research on attention and consciousness. Ongoing oscillations reflect functional states that bias processing of incoming signals through amplitude and phase. It is not known, however, whether the effect of phase or amplitude on stimulus processing depends on the long-term global dynamics of the networks generating the oscillations. Here, we show, using a computational model, that the ability of networks to regulate stimulus response based on pre-stimulus activity requires near-critical dynamics—a dynamical state that emerges from networks with balanced excitation and inhibition, and that is characterized by scale-free fluctuations. We also find that networks exhibiting critical oscillations produce differing responses to the largest range of stimulus intensities. Thus, the brain may bring its dynamics close to the critical state whenever such network versatility is required.

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

eLife Sciences Publications, Ltd

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Reference58 articles.

1. Distilling the neural correlates of consciousness;Aru;Neuroscience & Biobehavioral Reviews,2012

2. The decoupled mind: mind-wandering disrupts cortical phase-locking to perceptual events;Baird;Journal of Cognitive Neuroscience,2014

3. Self-organized criticality: an explanation of the 1/f noise;Bak;Physical Review Letters,1987

4. Neuronal avalanches in neocortical circuits;Beggs;The Journal of Neuroscience,2003

5. CircStat : a MATLAB toolbox for circular statistics;Berens;Journal of Statistical Software,2009

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