The meanings of 'function' in biology and the problematic case of de novo gene emergence-Reference-Cited by-同舟云学术

The meanings of 'function' in biology and the problematic case of de novo gene emergence

Published:2019-11-01 Issue: Volume:8 Page:
ISSN:2050-084X
Container-title:eLife
language:en
Short-container-title:

Author:

Keeling Diane Marie¹^ORCID,Garza Patricia²,Nartey Charisse Michelle³^ORCID,Carvunis Anne-Ruxandra⁴⁵^ORCID

Affiliation:

1. Department of Communication Studies, College of Arts & Sciences, University of San Diego, San Diego, United States

2. Colegio de Saberes, Mexico City, Mexico

3. Department of Biological Sciences, University of Texas at Dallas, Richardson, United States

4. Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, United States

5. Pittsburgh Center for Evolutionary Biology and Medicine, University of Pittsburgh School of Medicine, Pittsburgh, United States

Abstract

The word function has many different meanings in molecular biology. Here we explore the use of this word (and derivatives like functional) in research papers about de novo gene birth. Based on an analysis of 20 abstracts we propose a simple lexicon that, we believe, will help scientists and philosophers discuss the meaning of function more clearly.

Funder

National Institutes of Health

Kinship Foundation

Publisher

eLife Sciences Publications, Ltd

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://cdn.elifesciences.org/articles/47014/elife-47014-v1.pdf

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5. Proto-genes and de novo gene birth;Carvunis;Nature,2012

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