KCNE1 tunes the sensitivity of KV7.1 to polyunsaturated fatty acids by moving turret residues close to the binding site
Author:
Affiliation:
1. Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden
2. Department of Physiology and Biophysics, University of Miami, Miami, United States
Abstract
Funder
National Institutes of Health
Svenska Sällskapet för Medicinsk Forskning
Vetenskapsrådet
Linköping University
County Council of Östergötland
Lion Foundation
Publisher
eLife Sciences Publications, Ltd
Subject
General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience
Link
https://cdn.elifesciences.org/articles/37257/elife-37257-v2.pdf
Reference32 articles.
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2. Large-scale mutational analysis of Kv11.1 reveals molecular insights into type 2 long QT syndrome;Anderson;Nature Communications,2014
3. K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current;Barhanin;Nature,1996
4. KCNE1 and KCNE3 modulate KCNQ1 channels by affecting different gating transitions;Barro-Soria;PNAS,2017
5. Lipoelectric modification of ion channel voltage gating by polyunsaturated fatty acids;Börjesson;Biophysical Journal,2008
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