Synchronizing beta cells in the pancreas-Reference-Cited by-同舟云学术

Synchronizing beta cells in the pancreas

Published:2024-01-25 Issue: Volume:13 Page:
ISSN:2050-084X
Container-title:eLife
language:en
Short-container-title:

Author:

Peercy Bradford E¹^ORCID,Hodson David J²^ORCID

Affiliation:

1. Department of Mathematics and Statistics, University of Maryland Baltimore County (UMBC)

2. Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), NIHR Oxford Biomedical Research Centre, Churchill Hospital, Radcliffe Department of Medicine, University of Oxford

Abstract

The secretion of insulin from the pancreas relies on both gap junctions and subpopulations of beta cells with specific intrinsic properties.

Publisher

eLife Sciences Publications, Ltd

Link

https://cdn.elifesciences.org/articles/95103/elife-95103-v1.pdf

Reference10 articles.

1. New understanding of β-cell heterogeneity and in situ islet function;Benninger;Diabetes,2018

2. β-cell intrinsic dynamics rather than gap junction structure dictates subpopulations in the islet functional network;Briggs;eLife,2023

3. Connexin-36 gap junctions regulate in vivo first- and second-phase insulin secretion dynamics and glucose tolerance in the conscious mouse;Head;Diabetes,2012

4. Beta cell hubs dictate pancreatic islet responses to glucose;Johnston;Cell Metabolism,2016

5. PDX1LOW MAFALOW β-cells contribute to islet function and insulin release;Nasteska;Nature Communications,2021

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