Single cell, super-resolution imaging reveals an acid pH-dependent conformational switch in SsrB regulates SPI-2
Author:
Affiliation:
1. Mechanobiology Institute, T-Lab, National University of Singapore, Singapore, Singapore
2. Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, United States
Abstract
Funder
National Institutes of Health
Veteran's Affairs
Ministry of Education - Singapore
Ministry of Education
Publisher
eLife Sciences Publications, Ltd
Subject
General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience
Link
https://cdn.elifesciences.org/articles/45311/elife-45311-v2.pdf
Reference57 articles.
1. Bistable expression of virulence genes in salmonella leads to the formation of an antibiotic-tolerant subpopulation;Arnoldini;PLOS Biology,2014
2. pH-dependent secretion of SseB, a product of the SPI-2 type III secretion system of salmonella typhimurium;Beuzón;Molecular Microbiology,1999
3. The PhoP/PhoQ system controls the intramacrophage type three secretion system of salmonella enterica;Bijlsma;Molecular Microbiology,2005
4. Positive selection for loss of tetracycline resistance;Bochner;Journal of Bacteriology,1980
5. Structural and functional analysis of the C-terminal DNA binding domain of the salmonella typhimurium SPI-2 response regulator SsrB;Carroll;Journal of Biological Chemistry,2009
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