Redox takes control-Reference-Cited by-同舟云学术

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Redox takes control

Published:2024-06-20 Issue: Volume:13 Page:
ISSN:2050-084X
Container-title:eLife
language:en
Short-container-title:

Author:

Plaza-Menacho Iván¹^ORCID

Affiliation:

1. Kinases, Protein Phosphorylation and Cancer Group, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO)

Abstract

A study of two enzymes in the brain reveals new insights into how redox reactions regulate the activity of protein kinases.

Publisher

eLife Sciences Publications, Ltd

Link

https://cdn.elifesciences.org/articles/99765/elife-99765-v1.pdf

Reference15 articles.

1. Redox regulation of brain selective kinases BRSK1/2: Implications for dynamic control of the eukaryotic AMPK family through Cys-based mechanisms;Bendzunas;eLife,2024

2. Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity;Byrne;Science Signaling,2020

3. The cysteinome of protein kinases as a target in drug development;Chaikuad;Angewandte Chemie,2018

4. Structure-based design of a dual-warhead covalent inhibitor of FGFR4;Chen;Communications Chemistry,2022

5. An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function;Cuesta-Hernández;Nature Communications,2023

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